The Role of male sex hormone in Angiogenesis and Endothelial Progenitor Cell Mobilisatio

Phase 1

Recruiting

• Conditions: effect of androgen on formation of new blood vessels; Cardiovascular - Normal development and function of the cardiovascular system; Metabolic and Endocrine - Normal metabolism and endocrine development and function

• Registration Number: ACTRN12610000952044
• Lead Sponsor: Heart Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-11-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

all males, except for those aged 35-55 years old, and 18 is the minimum age

Exclusion Criteria

diabetes, prostate problem, on statin treatment, significant medical illness

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
endothelial progenitor cell functions assessment after treatment using in vitro assay (Asahara stain, Boyden chamber, and tubulogenesis assay), and in vivo model (cells transplanted to mice)[6 weeks after randomization (on completion of treatment)]

Secondary Outcome Measures

Name	Time	Method
effect on flow-mediated dilatation (FMD) of brachial artery using ultrasound[6 weeks after randomization (on completion of treatment)]