Comparative Effect Of Conventional and New Antiepileptic Drug Therapy On Serum Thyroid Profile In Adult Epileptic Patients
- Conditions
- Health Condition 1: null- EPILEPSY PATIENTS and HEALTHY VOLUNTEERS
- Registration Number
- CTRI/2017/12/010809
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 56
1 Patients aged between 18-60 years of age of either gender with epilepsy who are on stable dose of single antiepileptic drug for at least 6 months
2 Patients willing to give written informed consent
1 Patients on combination therapy with antiepileptic drugs
2 Patients who are noncompliant to the drug
3 Patients with history of progressive or psychiatric neurological disorder
4 Patients with refractory seizures
5 Patients who are on anti thyroid drugs or on thyroid hormone replacement therapy
6 Patients with other co morbid conditions like ischemic heart disease, stroke, chronic kidney disease, liver disease, diabetes mellitus, and hypertension and other metabolic diseases
7 Patients who had received the drugs, which could affect the level of thyroid hormones, in the past 6 months
8 pregnant and lactating mothers
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of Serum triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH)Timepoint: cross sectional study
- Secondary Outcome Measures
Name Time Method Measurement of Serum triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH)Timepoint: cross sectional study