The effect of airway pressure release ventilation on respiration and circulation in post-operative heart surgery patients
Not Applicable
Completed
- Conditions
- Postoperative pulmonary complications and cardiovascular complicationsRespiratory
- Registration Number
- ISRCTN92666776
- Lead Sponsor
- Sir Run Run Shaw Hospital
- Brief Summary
2021 Results article in https://doi.org/10.3389/fphys.2021.684927 (added 28/03/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. Age above 18
2.Received cardiothoracic surgery and needed invasive mechanical ventilation after admission to the ICU
Exclusion Criteria
1. Chronic obstructive pulmonary disease
2. Asthma
3. Mechanical ventilation pre-operation
4. Mechanical device to maintain hemodynamics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Electrical impedance imaging (EIT) was used to determine the difference in pulmonary gas distribution in patients undergoing cardiothoracic surgery before and after admission to the ICU after APRV
- Secondary Outcome Measures
Name Time Method <br> From patient records:<br> 1. Incidence of ventilator-associated pneumonia<br> 2. Incidence of atelectasis<br> 3. Duration of mechanical ventilation<br> 4. Length of ICU stay<br> 5. Final outcome (death/survival)<br>