Comparative clinical study on the effect of Doorvadi Ghrita And Shatadhauta Ghrita Guda Pichu In Parikartika (Fissure-In-Ano)
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To see the reduction in Pain, Constipation, Bleeding
研究概览
简要总结
Fissure in ano which is described as Parikartika in Ayurveda, is a very common and the most painful condition occurring in Ano-rectal region in day-to-day life. Incidence is around 1 in 350 adults and most often occur in adults aged 15-40 years. Parikartika is characterized with Kartanavat Shoola, Daha and Anilasanga in the region of Guda, Nabhi, and Medra along with Aruchi. Importance is laid because of its higher recurrence rates.
Parikartika has reference in all the Brihatrayees not as a separate entity, but as a complication of improper administration of treatmemt procedures like Virechana, Bastikarma Vyapad and as a complication of diseases like Atisara, Grahani and Udavarta caused by vitiation of Vata & Pitta.
Chikitsa for Parikartika mentioned by Charaka are Pichu with Sarpi and Pichha Basti. Keeping this point of view, the present study focuses on evaluating the comparative effectiveness of Doorvadi Ghrita and Shatadhauta Ghrita in Parikartika to reduce pain, bleeding, burning sensation, sphincter spasm and promotes ulcer healing. Shatadhauta Ghrita and Doorvadi Ghrita are selected as they are having effective Vrana Ropana and Vrana Shodhana properties.
OBJECTIVE**:** To compare the effectiveness Of Doorvadi Ghrita Guda Pichu with Shatadhauta Ghrita Guda Pichu in the Management of Parikartika (Fissure in Ano).
METHODOLOGY: Interventional clinical study
Sample size: 40
Groups**:** 2; 20 subjects in each group
Group A- Taken as Standard group for Guda Pichu of Doorvadi Ghrita.
Group B- Taken as Trial group for Guda Pichu of Shatadhauta Ghrita.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Spasm of Anal sphincter Presence of Fissure-in-ano.
- •Patients willing to participate and sign the informed consent form.
排除标准
- •Patients with K/C/O Ulcerative colitis, Crohn’s disease, Tuberculosis Patient with Carcinoma of rectum & anal canal Patients with other systemic illness like uncontrolled diabetes mellitus (HbA1c > 8%), HIV and HBsAg positive patients.
结局指标
主要结局
To see the reduction in Pain, Constipation, Bleeding
时间窗: To see the reduction in Burning Sensation after 7th,14th and 28 days
次要结局
- Size of ulcer(Sphincter tone)