Guda Pichu

Phase 1/2

Not yet recruiting

Conditions: Anal fissure, unspecified. Ayurveda Condition: PARIKARTIKA,

Registration Number: CTRI/2022/08/044858

Lead Sponsor: Sri Dharmasthala College of Ayurveda and Hospital B M Road Thanniruhalla Hassan Karnataka

Brief Summary: Fissure in ano which is described as Parikartika in Ayurveda, is a very common and the most painful condition occurring in Ano-rectal region in day-to-day life. Incidence is around 1 in 350 adults and most often occur in adults aged 15-40 years. Parikartika is characterized with Kartanavat Shoola, Daha and Anilasanga in the region of Guda, Nabhi, and Medra along with Aruchi. Importance is laid because of its higher recurrence rates.

Parikartika has reference in all the Brihatrayees not as a separate entity, but as a complication of improper administration of treatmemt procedures like Virechana, Bastikarma Vyapad and as a complication of diseases like Atisara, Grahani and Udavarta caused by vitiation of Vata & Pitta.

Chikitsa for Parikartika mentioned by Charaka are Pichu with Sarpi and Pichha Basti. Keeping this point of view, the present study focuses on evaluating the comparative effectiveness of Doorvadi Ghrita and Shatadhauta Ghrita in Parikartika to reduce pain, bleeding, burning sensation, sphincter spasm and promotes ulcer healing. Shatadhauta Ghrita and Doorvadi Ghrita are selected as they are having effective Vrana Ropana and Vrana Shodhana properties.

**OBJECTIVE****:** To compare the effectiveness Of Doorvadi Ghrita Guda Pichu with Shatadhauta Ghrita Guda Pichu in the Management of Parikartika (Fissure in Ano).

**METHODOLOGY:** Interventional clinical study

**Sample size**: 40

**Groups****:** 2; 20 subjects in each group

Group A- Taken as Standard group for Guda Pichu of Doorvadi Ghrita.

Group B- Taken as Trial group for Guda Pichu of Shatadhauta Ghrita.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

Spasm of Anal sphincter Presence of Fissure-in-ano.
Patients willing to participate and sign the informed consent form.

Exclusion Criteria

Patients with K/C/O Ulcerative colitis, Crohnâ€™s disease, Tuberculosis Patient with Carcinoma of rectum & anal canal Patients with other systemic illness like uncontrolled diabetes mellitus (HbA1c > 8%), HIV and HBsAg positive patients.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To see the reduction in Pain, Constipation, Bleeding	To see the reduction in Burning Sensation after 7th,14th and 28 days

Secondary Outcome Measures

Name	Time	Method
Size of ulcer	Sphincter tone

Trial Locations

Locations (1): Sri Dharmasthala College of Ayurveda and Hospital B M Road Thanniruhalla Hassan Karnataka
🇮🇳
Hassan, KARNATAKA, India
Sri Dharmasthala College of Ayurveda and Hospital B M Road Thanniruhalla Hassan Karnataka
🇮🇳Hassan, KARNATAKA, India
Dr Chaturbhuj
Principal investigator
9992185529
chaturbhujmehra@gmail.com