Role of leptin in Polycystic ovarian syndrome and effect of metformin therapy on its levels.
Phase 4
- Conditions
- Health Condition 1: null- Polycystic ovary syndrome
- Registration Number
- CTRI/2012/07/002806
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
For Group 1- Newly diagnosed PCOS
For group 2- Normally cycling
BMI matched
Exclusion Criteria
For Group 1- Any other known cause of amenorrhea
Taking concomitant medication for PCOS
Known hypersensitivity to Metformin
Chronic heart, pulmonary, kidney, liver disease
Uncontrolled diabetes with possibility of DKA
For Group 2- Any chronic systemic illness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br/ ><br>a)To compare Leptin concentration in PCOS patients with BMI controlled normally cycling healthy women. <br/ ><br>b)To correlate serum Leptin level with clinical and biochemical indicators of PCOS patients <br/ ><br>Timepoint: 3 months
- Secondary Outcome Measures
Name Time Method To evaluate effect of Metformin on Leptin level in PCOS patients.Timepoint: 3 months