Evaluation of the effect of hormone therapy in breast cancer before surgery
Phase 3
Recruiting
- Conditions
- Breast cancer.Malignant neoplasm of breast, endocrine therapy, neoadjuvant
- Registration Number
- IRCT20181224042091N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 48
Inclusion Criteria
female with invasive breast cancer with positive hormone receptor and negative HER2 proven in pathology
Clinical Phase IIA to IIIC (T1-4, N0-3, M0)
Age more than 18 years
Good performance ((ECOG: 0-1
No history of previous chemotherapy
It is a conscientious informed consent
Exclusion Criteria
Pregnancy / Breastfeeding
Liver cirrhosis
History of thromboembolic events in the patient
History of osteoporotic fractures
Patient's lack of cooperation in correct implementation of the treatment process in accordance with the recommended guidelines
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical response rate. Timepoint: Clinical examination before and after treatment of Neo-adjuvant. Method of measurement: clinical examination and Sonography.
- Secondary Outcome Measures
Name Time Method Pathologic response. Timepoint: after surgery. Method of measurement: pathologic response rate.