Multidisciplinary Approach to Reduce Injury and Substance Abuse

Phase 3

Completed

• Conditions: Drug Abuse
• Interventions: Behavioral: Brief advice; Behavioral: Brief Intervention plus Booster; Behavioral: Brief Intervention

• Registration Number: NCT01048359
• Lead Sponsor: University of Texas at Austin

Brief Summary

The primary purpose of the project entitled: Multidisciplinary Approach to Reduce Injury and Substance Abuse, which is funded by the National Institute on Drug Abuse (5R01DA026088-02), is to compare the effectiveness of brief intervention, brief intervention plus a booster, and brief advice for adult patients who abuse drugs and present to a trauma department for treatment of an injury.

Detailed Description

Multidisciplinary Approach to Reduce Injury and Substance Abuse is a randomized clinical trial evaluating the effectiveness of brief advice (BA), brief motivational intervention with feedback (BMI), and brief motivational intervention with feedback and booster (BMI+B) in injured patients with drug problems.

The setting is a level 1 Trauma Department, which serves a large and diverse patient population. Injured patients are screened for eligibility in the project based on a positive toxicology screen or self reported drug use in the past 90 days. The primary outcome of interest will be patients' subsequent drug use. Other outcomes of interest include: HIV-related risk behaviors, improved health outcomes (including injury reduction), increased employment, decreased engagement in illegal behavior, increased substance abuse treatment utilization, and enhanced quality of life at three, six, and twelve month follow-ups.

This study will also examine the potential moderating and mediating effects of patient readiness to change, use of experiential and behavioral processes of change and decisional balance considerations. In addition, this project will examine implementation factors at the organizational level and the cost effectiveness of BA, BMI, and BMI+B.

Study participants and their related identifying information will be collected during the time they are admitted to the recruitment hospital trauma department. Study participants must be 18 years or older, speak English or Spanish, have been admitted to the recruitment hospital trauma department, and test positive for illegal drugs or admit to illegal drug use when verbally screened. Additional information will be collected from participants in the in-person assessment interviews at three, six, and 12 month follow-up periods.

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2010-01-11
• Study First Submitted QC: 2010-01-11
• Study First Posted: 2010-01-13
• Primary Completion: 2014-04
• Study Completion: 2015-06
• Status Verified: 2015-11
• Last Update Submitted: 2015-11-23
• Last Update Posted: 2015-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 417

Inclusion Criteria

• Study participants must be 18 years or older
• Speak English or Spanish
• Been admitted to the level 1 Trauma Department
• Test positive for illegal drugs or admit to illegal drug use

Exclusion Criteria

• Other penetrating trauma not related to motor vehicle collisions, violence or falls, such as poisoning and, bites
• Patients with traumatic brain injury, or a Glasgow Coma Scale score of less than 15
• Patients who do not pass the Mini-Mental Status Exam are excluded

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Brief advice	Brief advice	This condition of the experiment acts a control and will be a short session in which the therapist will provide brief advice about drug use and give the patient a pamphlet.
Brief Intervention plus Booster	Brief Intervention plus Booster	30-45 minute motivational interviewing based intervention with feedback addressing drug use, injury prevention and HIV risk plus a brief phone booster session at 1 month post-intake to review feedback, 2) assess progress, 2) renew motivation to change, and 3) evaluate and affirm commitment to change.
Brief Intervention	Brief Intervention	30-45 minute motivational interviewing based intervention with feedback addressing drug use, injury prevention and HIV risk.

Primary Outcome Measures

Name	Time	Method
The primary outcome of interest will be patients' subsequent drug use.	3, 6, and 12 months after intervention

Secondary Outcome Measures

Name	Time	Method
HIV risk-behaviors, improved health, increased employment, decreased illegal behavior, increased substance treatment, enhanced quality of life, use of Transtheoretical model of change, organization implementation, and intervention cost-effectiveness.	3, 6, and 12 months after intervention

Trial Locations

Locations (1)

University Medical Center Brackenridge; 🇺🇸 Austin, Texas, United States