Effect of High Intensity Interval Training with Blood Flow Restriction on cardiovascular function of Cardiotoxic patients after Breast Cancer therapy

Not Applicable

• Conditions: Condition 1: Cardiotoxicity. Condition 2: Cardiac rehabilitation. Condition 3: Breast Cancer.; Cardiomyopathy due to drug and external agent; Malignant neoplasm of breast; Therapeutic (nonsurgical) and rehabilitative cardiovascular devices associated with adverse incidents; I42.7; Y71.1

• Registration Number: IRCT20200412047045N1
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

Breast Cancer patients
Age < 65y
Second phase of rehabilitation
Without Cardiac diseaes before Cancer Treatment
Treatment Drug: Anthracyclines
40 =Ejection Fraction= 50
Heart failure treatment: Beta blockers, ACEI
Permission of Cardiologist
Signature of consent letter

Exclusion Criteria

Conditions that cause the patient, not be able to perform the exercises(Fracture of limbs, pregnancy,…)
Symptoms of severe heart failure
Sign of recurrence of breast cancer (repeat chemotherapy)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cardiovascular function. Timepoint: before intervention and after 12 weeks after intervention. Method of measurement: echocardiography.

Secondary Outcome Measures

Name	Time	Method
ew York Heart Association (NYHA) Functional Classification. Timepoint: before and after 12 weeks intervention. Method of measurement: the New York Heart Association (NYHA) Functional Classification. It places patients in one of four categories based on how much they are limited during physical activity.