Comparing surgically placed jejunal tubes with nasal tubes for feeding in patients undergoing surgery for food pipe cancer.

Recruiting

Conditions: Malignant neoplasm of esophagus, unspecified,

Registration Number: CTRI/2020/05/025445

Brief Summary: Early enteral nutrition is one of the key goals and is preferred over parenteral nutrition following oesophagectomy. It improves postoperative outcomes by maintaining gut mucosal integrity and improving immunological functioning. Feeding jejunostomy as a means of enteral access is being used routinely at many centres, but is associated with complications. Nasojejunal tube feeding is an alternative access route to establish enteral nutrition. There has been only one randomized control trial in patients with oesophageal cancer, in a western population, comparing feeding jejunostomy with nasojejunal tube feeding. There exists a paucity of studies in the Asian population, evaluating the safety and efficacy of nasojejunal tube feeding. We aim to compare feeding jejunostomy with nasojejunal tube feeding in terms of efficacy and complications in Indian patients undergoing gastric/colonic pull-up and cervical oesophageal anastomosis for carcinoma oesophagus.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 40

Inclusion Criteria

All patients undergoing oesophagectomy for carcinoma oesophagus.

Exclusion Criteria

1.Those who refuse consent to participate in the study 2.Patients with any nasopharyngeal or oropharyngeal obstruction preventing insertion of nasojejunal tube.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of complications in both groups of patients: those undergoing nasojejunal tube feeding versus surgical feeding jejunostomy	Post operatively, till the time of removal of feeding jejunostomy tube at 6 weeks.

Secondary Outcome Measures

Name	Time	Method
1.To compare catheter efficacy of nasojejunal tube feeding with surgical feeding jejunostomy in terms of:	Time to full establishment of oral intake
2.To compare the discomfort associated with surgical feeding jejunostomy versus nasojejunal tube using the visual analogue scale.	From post operative day 2 till the time of removal of nasojejunal tube
3.To compare the quality of life with a surgical feeding jejunostomy with nasojejunal feeding tube using the WHOQOL-BREF questionnaire	Self reported at the time of discharge and at 6 weeks follow up.

Trial Locations

Locations (1): AIIMS, New Delhi
🇮🇳
Delhi, DELHI, India
AIIMS, New Delhi
🇮🇳Delhi, DELHI, India
Dr Lokesh Agarwal
Principal investigator
9910499609
devloksang@gmail.com