Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA
Not yet recruiting
- Conditions
- Male Infertility Due to Azoospermia
- Registration Number
- NCT06307639
- Lead Sponsor
- Assiut University
- Brief Summary
* Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).
* Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- Male
- Target Recruitment
- 64
Inclusion Criteria
- Infertile males with normal volume, functional (non-obstructive) azoospermia.
- Age: 18-45 years
Exclusion Criteria
- Patients with proven obstructive azoospermia.
- Cryptorchidism.
- Testicular Agenesis and testicular atrophy.
- Patient with exposure to gonadal toxins like chemotherapy, radiotherapy, and alkylating agents.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detect if PGK2 and/or AVRV1 level can used as predictor for spermatogenesis in infertile men with non-obstructive azoospermia undergoing Testicular Sperm Extraction. 2 years Know more about the functional role of PGK2 and ACRV1 in the process of spermatogenesis. 2 years
- Secondary Outcome Measures
Name Time Method