NCT06307639尚未招募不适用
Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 64
- 主要终点
- Detect if PGK2 and/or AVRV1 level can used as predictor for spermatogenesis in infertile men with non-obstructive azoospermia undergoing Testicular Sperm Extraction.
研究概览
简要总结
- Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).
- Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Infertile males with normal volume, functional (non-obstructive) azoospermia.
- •Age: 18-45 years
排除标准
- •Patients with proven obstructive azoospermia.
- •Cryptorchidism.
- •Testicular Agenesis and testicular atrophy.
- •Patient with exposure to gonadal toxins like chemotherapy, radiotherapy, and alkylating agents.
结局指标
主要结局
Detect if PGK2 and/or AVRV1 level can used as predictor for spermatogenesis in infertile men with non-obstructive azoospermia undergoing Testicular Sperm Extraction.
时间窗: 2 years
Know more about the functional role of PGK2 and ACRV1 in the process of spermatogenesis.
时间窗: 2 years
次要结局
未报告次要终点
研究者
Muhammad Yousef Muhammad Swifee
Assistant lecturer of Andrology ,Sexology and STIs
Assiut University
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