To compare the effect of putting lignocaine inside the cuff and applying water soluble gel on the outer surface of cuff of tube in windpipe with putting lignocaine alone inside the cuff on sore throat after operatio
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/02/062490
- Lead Sponsor
- VMMC and Safdarjung Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of age 18 to 65 years, of American Society of Anaesthesiologist physical status I or II, expected to undergo elective surgery of more than 2 hours duration, under general
anaesthesia requiring orotracheal intubation.
Exclusion Criteria
1. Patients with history of cough, sore throat or respiratory disease, smokers, difficult
airway, modified Mallampati class 3 or 4.
2. Patients undergoing head, neck and upper airway surgeries, expected to have a difficult extubation or postoperative elective ventilation.
3. Patients allergic to study drug or receiving lignocaine in any other form.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of intracuff 2% alkalinized lignocaine and water-soluble gel <br/ ><br>lubrication with intracuff saline and intracuff 2% alkalinized lignocaine on the incidence of <br/ ><br>postoperative sore throat at 1 hour following extubation.Timepoint: At 1 hour post extubation
- Secondary Outcome Measures
Name Time Method To compare the incidence of emergence cough and agitation. <br/ ><br>To compare the haemodynamic response to extubation. <br/ ><br>To compare the incidence of sore throat at 24 h.Timepoint: At 24 hour post extubation