A study of musk in the treatment of microcirculation disorder after PPCI in acute ST-segment elevation myocardial infarctio
- Conditions
- Acute ST-segment elevation myocardial infarction
- Registration Number
- ITMCTR2000003817
- Lead Sponsor
- onghua Hospital affiliated to Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) AMI met WHO diagnostic criteria: persistent chest pain >30 minutes; Myocardial enzymes increased twice the normal value; St-segment elevation of two adjacent leads on the electrocardiogram >0.1mv;
(2) Patients with first myocardial infarction;
(3) Coronary angiography was performed to confirm complete occlusion of the criminal's blood vessels and direct PCI was performed;
(4) All patients took aspirin, Bolivar, statins, lipid-lowering drugs and other drugs to inhibit in-stent restenosis as prescribed by the doctor after surgery;
(5) No angina attack.
1. Patients with coagulation dysfunction and severe liver and kidney dysfunction;
2. Patients with heart disease, severe pulmonary hypertension, uncontrolled hypertension, and adults with right-to-left shunt
3. Patients with suction distress syndrome;
4. With other heart diseases, such as rheumatic heart disease, congenital heart disease, etc.;
5. Severe arrhythmia, including frequent pre-ventricular contraction, paroxysmal ventricular tachycardia, atrial fibrillation;
6. A history of drug allergy.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TIMI myocardial perfusion framecount, TMPFC;Coronary Flow Reserve;Thrombolysis In Myocardial Infarction,TIMI;Symptomatology of Chinese medicine;cardiac function;ST segment recovery degree of ECG;index of microcirculatory resistance;
- Secondary Outcome Measures
Name Time Method