Endometrial Scratching in Couples With Unexplained Subfertility

Phase 2

Completed

• Conditions: Subfertility
• Interventions: Procedure: scratching

• Registration Number: NCT01412606
• Lead Sponsor: Mansoura University

Brief Summary

Endometrial scratching in luteal phase of a spontaneous menstrual cycle may increase pregnancy rate in women with unexplained infertility.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-07
• Primary Completion: 2010-12
• Study Completion: 2011-06
• Study First Submitted: 2011-08-08
• Study First Submitted QC: 2011-08-08
• Study First Posted: 2011-08-09
• Status Verified: 2012-08
• Last Update Submitted: 2012-08-28
• Last Update Posted: 2012-08-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 105

Inclusion Criteria

• women aged between 20 and 39 years with at least one year of infertility
• regular menstruation with the length of the cycle between 22-34 days and ovulation confirmed by appropriately timed mid-luteal progesterone
• fertile semen variables
• bilateral tubal patency (demonstrated by laparoscopy or hysterosalpingography).

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Scrathcing	scratching	scratching of endometrium on day 21-26 of a spontaneous menstrual cycle
Control	scratching	Uterine sounding on day 21-26 of a spontaneous menstrual cycle

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate	6 months

Secondary Outcome Measures

Name	Time	Method
miscarriage rate	6 months

Trial Locations

Locations (1)

Mansoura University Teaching Hospital Gynecology outpatient clinic; 🇪🇬 Mansoura, Egypt