The relation between increased platelet reactivity during PCI and peri-procedural myocardial injury: comparison of clopidogrel with prasugrel
Not Applicable
- Conditions
- effort angina
- Registration Number
- JPRN-UMIN000027582
- Lead Sponsor
- Okayama City Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
Not provided
Exclusion Criteria
hemorrhagic tendency severe liver dysfunction(child-pugh grade C) severe renal dysfunction (eGFR <30mL/min/1.73m2) severe hypertension (systolic blood pressure >180) have past history of cerebral infarction or transient ischemic attack have intolerance with other thienopyridine derivative
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the occurrence rate of PMI (definition of PMI) High-sensitive Troponin-T (hs-TnT) was measured before and 24 hours after PCI. In patients with normal (<99th percentile URL) baseline hs-TnT concentrations, PMI was defined as elevation of hs-TnT >5*99th percentile URL 24 hours after PCI. If the baseline hs-TnT values are elevated and are stable or falling, then a rise of > 20% is required for the diagnosis of PMI.
- Secondary Outcome Measures
Name Time Method PRU value before and after PCI. the serial change in platelet reactivity during elective PCI. the correlation between the occurrence of PMI and PRU value before PCI and after PCI. cardiovascular event and hemorrhagic event within 30 days after PCI.