Investigation of Anatomical Correlates of Speech Discrimination
- Conditions
- Sensorineural Hearing Loss
- Registration Number
- NCT01781039
- Brief Summary
Understanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to determine the relative importance of the sensory cells of the inner ear and auditory neurons on speech discrimination performance in quiet and in noise. This information may be used as a predictor of hearing aid benefit. The investigators expect to find decreased speech understanding ability resulting from both loss of sensory cells and the loss of auditory neurons.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1652
- Normal hearing to moderate sensorineural hearing loss
- Sufficient English proficiency to complete speech discrimination testing in English
- Hearing loss less than a 45 dB HL pure tone average (average hearing thresholds at 500, 1000 and 2000 Hz)
- Conductive hearing loss
- Neurodegenerative disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Regression analysis June 2024 Regression analysis will be used to look for a correlation between measures of sensory cell and auditory neuron survival and speech recognition performance.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Steward St. Elizabeth's Medical Center
🇺🇸Brighton, Massachusetts, United States
Steward St. Elizabeth's Medical Center🇺🇸Brighton, Massachusetts, United States