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临床试验/EUCTR2016-000237-48-NL
EUCTR2016-000237-48-NL进行中(未招募)1 期

The effect of Mirabegron on brown adipose tissue in healthy young white Caucasian and South Asian men - MiraBAT study

eiden University Medical Center0 个研究点目标入组 20 人开始时间: 2016年2月11日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
Male

入选标准

  • Male volunteers. 10 white Caucasians, born in the Netherlands. 10 South Asians, living in the Netherlands.
  • Age: 18-30 years
  • BMI = 25 kg/m2
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 20
  • F.1.3 Elderly (>=65 years) no
  • F.1.3.1 Number of subjects for this age range

排除标准

  • BMI > 25 kg/m2
  • Recent excessive weight loss or exercise
  • Alcohol and/ or drugs abuse
  • Excessieve smoking (>10 cigarettes/day)
  • Any significant chronic disease, including diabetes, Renal, hepatic or endocrine disease
  • Heart disease or arrhythmias
  • Thyroid disease or thyroid medication
  • Hypertension
  • Use of medication known to influence glucose and/or lipid metabolism or BAT activity (e.g. beta blockers or calcium channel blockers)
  • Use of drugs that influence cardiac function or affect QT time
  • Use of MAO inhibitor
  • Use of systemic corticosteroids in previous six weeks
  • Recent participation in other research projects (within the last 3 months), participation in 2 or more projects in one year
  • Contraindications for undergoing an MRI scan.

研究者

发起方
eiden University Medical Center

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