The effect of prolonged and repeated moderate-intensity exercise on inflammation in patients with Inflammatory Bowel Disease

Completed

• Conditions: Inflammatory Bowel Disease; Crohn's disease; Ulcerative Colitis

• Registration Number: NL-OMON27563
• Lead Sponsor: Wageningen University / Radboudumc, Nijmegen

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

IBD subjects:
- Diagnosis of Crohn’s disease or ulcerative colitis (total or left-sided colitis) made by gastroenterologist
- 18 years of age or older
- Participation in Nijmegen Four Day Marches, edition 2019

Healthy subjects:
- 18 years of age or older
- Participation in Nijmegen Four Day Marches, edition 2019

Exclusion Criteria

IBD subjects:
- Use of biologicals (e.g. infliximab, adalimumab, golumimab, ustekinumab)

Healthy subjects:
- History of IBD or other gastro-intestinal diseases such as celiac disease or Irritable Bowel Syndrome (IBS)
- History of significant systemic diseases, such as diabetes mellitus, cancer, cardiovascular or respiratory disease, that may have an effect on study outcomes

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in gastrointestinal inflammation measured by faecal calprotectin.

Secondary Outcome Measures

Name	Time	Method
Changes in:<br>- Inflammatory markers in blood<br>- Clinical disease activity