Effect of Total Intravenous Anesthesia and Balanced Anesthesia on Postoperative Lung Function

Phase 4

Completed

• Conditions: Lung Function
• Interventions: Drug: propofol; Drug: remifentanil; Drug: fentanyl; Drug: Sevoflurane/Nitrous Oxide

• Registration Number: NCT00706277
• Lead Sponsor: Medical University Innsbruck

Brief Summary

The aim of the study is to investigate the effects of total intravenous anesthesia (TIVA; propofol, remifentanil) and balanced anesthesia (BAL; induction with propofol and fentanyl; maintenance of anesthesia with sevoflurane and nitrous oxide) on pulmonary function 30 minutes after emergence from the general anesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-06
• Study First Submitted: 2008-06-25
• Study First Submitted QC: 2008-06-26
• Study First Posted: 2008-06-27
• Study Completion: 2008-12
• Status Verified: 2009-02
• Last Update Submitted: 2009-02-09
• Last Update Posted: 2009-02-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA 1-2
• BMI normal

Exclusion Criteria

• lung disease
• Nicotine abuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
balanced	Sevoflurane/Nitrous Oxide	patients receiving balanced anesthesia
TIVA	propofol	patients receiving total intravenous anesthesia (TIVA)
TIVA	remifentanil	patients receiving total intravenous anesthesia (TIVA)
balanced	propofol	patients receiving balanced anesthesia
balanced	fentanyl	patients receiving balanced anesthesia

Primary Outcome Measures

Name	Time	Method
FEV1 forced expiratory volume; FVC forced vital capacity	preoperative, 30 minutes postoperative

Trial Locations

Locations (1)

TILAK Hospitals; 🇦🇹 Innsbruck, Austria