A pilot study to evaluate AMPA receptors densities in striatum with [11C]K-2 PET imaging in Parkinson's disease.

Not Applicable

Recruiting

• Conditions: Parkinson's disease

• Registration Number: JPRN-jRCTs031200448
• Lead Sponsor: Abe Hiroki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-29
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. 40 years old older and younger than 81 years old at the registration
2. Diagnosed as clinically established Parkinson's disease with MDS PD criteria 2015.
3. Underwent DAT SPETC within a year.
4. Patients who can express intents to participate in this research with written documents.
A person who decides to participate in this research at his / her own free will can obtain written consent. However, when the consent explanation document cannot be read or written by the disease's symptoms, a witness will give his/her written consent. The witnesses are adults who are not unduly affected by those involved in this study and can take a third-party position. When he/she can not provide informed consent, it is possible to provide written consent with the substitute person's signature. A substitute person is an adult who is equivalent to his / her spouse, parents, compatriots, children, family members living together, or close relatives and can represent the will and interests.

Exclusion Criteria

1. Patients who can not anwser their name, birth date or current month.
2. Patients who have a history of epilepsy.
3. Patients with dyalysis.
4. Patients who can not undergo head 3T-MRI.
5. Patietnts who underwent non-invasive brain stimulation therapy within a year.
6. Patients who have symptoms which could not be explained by PD.

Study & Design

• Study Type: Interventional
• Study Design: Not specified