Comparative effects of 2 types of hormone replacement therapy on climacteric symptoms
Phase 3
- Conditions
- menopause.Menopausal and female climacteric states
- Registration Number
- IRCT138809032766N1
- Lead Sponsor
- Tarbiat Maodares University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
married, menopause after 40 years old and 12 months amenorrhea or 6 month amenorrhea and serum Estradiol less than 50 pg/dl.
Exclusion criteria: any history of active hepatitis, cardiovascular, inflamation disease (infectious or uninfectious), thoromboambolic or cerebrovascular disorder, psychosis, hyperlipidemia, history of chemotherapy or radiation, HRT treatment in previous 6 months, use of vitamine E, fluxitine, soymenopause,propranolol and another herbal or chemical druge, smoking, alchol or addiction
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Climacteric symptom. Timepoint: 6 month. Method of measurement: Greene Climacteric Scale & Female Sexual Function Index.
- Secondary Outcome Measures
Name Time Method Sex hormone status & sex hormone-binding globulin (SHBG). Timepoint: 6 month. Method of measurement: biochemistry.