Auditory Stimulation Effect on Brain Oscillations and Sleep Dependent Learning
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Sleep spindle rate
研究概览
简要总结
The investigators are testing the impact of quiet sounds played during sleep on brain oscillations and memory.
详细描述
Participants will undergo two visits with a memory task and nap. During one of the visits, quiet sounds will be played timed with sleep oscillations. During the other visit, no sounds will be played. Brain oscillations and memory will be measured at each visit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •History of neurological disease, psychiatric disease, sleep apnea or sleep disorder.
研究组 & 干预措施
Auditory Stimulation
Quiet sounds are played during sleep
干预措施: Quiet Sounds (Other)
结局指标
主要结局
Sleep spindle rate
时间窗: 90 minutes
Sleep spindles are prominent thalamocortical brain oscillations seen on EEG during sleep that have been mechanistically linked to sleep-dependent memory consolidation. The sleep spindle rate over the course of the nap will be assessed using an automated spindle detector applied to the collected EEG sleep data.
次要结局
- Memory consolidation(90 minutes)
研究者
Catherine Chu, MD
Associate Professor, Neurology
Massachusetts General Hospital