Auditory Stimulation Effect on Brain Oscillations and Sleep Dependent Learning
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy Control
- Sponsor
- Massachusetts General Hospital
- Enrollment
- 40
- Primary Endpoint
- Sleep spindle rate
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
The investigators are testing the impact of quiet sounds played during sleep on brain oscillations and memory.
Detailed Description
Participants will undergo two visits with a memory task and nap. During one of the visits, quiet sounds will be played timed with sleep oscillations. During the other visit, no sounds will be played. Brain oscillations and memory will be measured at each visit.
Investigators
Catherine Chu, MD
Associate Professor, Neurology
Massachusetts General Hospital
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •History of neurological disease, psychiatric disease, sleep apnea or sleep disorder.
Outcomes
Primary Outcomes
Sleep spindle rate
Time Frame: 90 minutes
Sleep spindles are prominent thalamocortical brain oscillations seen on EEG during sleep that have been mechanistically linked to sleep-dependent memory consolidation. The sleep spindle rate over the course of the nap will be assessed using an automated spindle detector applied to the collected EEG sleep data.
Secondary Outcomes
- Memory consolidation(90 minutes)