TARGET Protein: The effect of augmented administration of enteral protein to critically ill adults on clinical outcomes: A cluster randomised, cross-sectional double cross-over, registry-embedded, pragmatic clinical trial

Not Applicable

Completed

• Conditions: Critical Illness; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12621001484831
• Lead Sponsor: Central Adelaide Local Health Network

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-01
• Study Completion: 2023-11-22
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3412

Inclusion Criteria

1) About to commence enteral nutrition

Exclusion Criteria

1.The treating clinician considers the study formulae to be contraindicated
2.The patient has previously participated in TARGET Protein Trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Days free of the index hospital and alive at day-90<br><br>(Calculated as 90 and subtracting all days in hospital during the index hospital admission plus any readmissions to the index hospital within 90 days for which the patient remains in-hospital at 2400 h. Patients will be considered alive if they are alive at discharge from the index-hospital and there is no evidence of death before day 90 and after hospital death from the national death index. All deaths up to day 90 counted as zero days free of index hospital and alive at day-90).[ Censored at 90 days following commencement of enteral nutrition (intervention EN or control EN)]