Inspiratory muscle training in patients with Chronic Obstructive Pulmonary Disease (COPD)
Completed
- Conditions
- Chronic obstructive pulmonary diseaseRespiratoryOther chronic obstructive pulmonary disease
- Registration Number
- ISRCTN19258620
- Lead Sponsor
- HS R&D Regional Programme Register - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. 80 non-hypercapnic patients with moderate (forced expiratory volume [FEV] <40%) will be recruited from consultant hospital and community chest clinics.
2. All patients will be receiving optimum medical management and will have been stable for at least 4 weeks prior to their initial assessment.
Exclusion Criteria
1. Hypercapnia (PaCO2 >45 mmHg)
2. Any patient who is unsuitable for magnetic stimulation (pacemakers, artificial heart valves, metal prosthesis).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean changes in respiratory muscle strength (cms H2O), respiratory muscle endurance (peak power [cms H2O] and duration [seconds]), shuttle walk distance (metres), Borg scores for breathlessness and CRDQ will be compared between groups using an unpaired t-test or analysis of covariance. Any changes in respiratory muscle strength and endurance will be compared with changes in shuttle walk distance and CRDQ scores using correlation.
- Secondary Outcome Measures
Name Time Method ot provided at time of registration