DRKS00007644
Completed
未知
Influence of effective noninvasive positive pressure ventilation on biomarkers in stable hypercapnic COPD patients
Firma Resmed0 sites20 target enrollmentJanuary 23, 2015
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- J44.9
- Sponsor
- Firma Resmed
- Enrollment
- 20
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •COPD patients in stadium GOLD iV with hypercapnia (PaCO2 \> 50 mmHg)
- •Stable state of disease (pH \>7,33\)
Exclusion Criteria
- •Severe Obesity (BMI \> 35 kg/m2\)
- •Restrictive lung disease (total lung capacity \<80%)
- •Acute infections including acute pulmonary exacerbation
- •Chronic inflammatory diseases other than COPD or atherosclerosis that could be potential confounders (e.g. rheumatic disease, collagenoses, etc.)
- •Malignant disease
- •Anti\-inflammatory or immunosuppressive drugs other than statins, aspirin or clopidogrel
Outcomes
Primary Outcomes
Not specified
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