Delayed cord clamping in preterm neonates 30 to 33 weeks: A randomized controlled trial
Not Applicable
- Conditions
- Health Condition 1: null- preterm neonates at birth
- Registration Number
- CTRI/2014/02/004414
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 434
Inclusion Criteria
1)Imminently delivering mothers from 30 weeks to 33 6/7 weeks
2)Parents have given informed consent.
Exclusion Criteria
1)Major congenital malformation incompatible for life diagnosed or suspected antenatally
2)Multiple pregnancy
3)Conditions where placental transfusion by delaying cord clamping could further compromise the just delivered neonate due to the additional blood volume being transfused such as antenatally diagnosed hydrops fetalis (irrespective of etiology or type of hydrops)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method composite outcome measure of all cause mortality and/or abnormal neurological examination at 40 weeks postnatal ageTimepoint: At 40 weeks postnatal age
- Secondary Outcome Measures
Name Time Method Incidence of following at 40 weeks postnatal age : <br/ ><br>1. All cause mortality <br/ ><br>2. Intraventricular hemorrhage <br/ ><br>3. bronchopulmonary dysplasia <br/ ><br>4. Necrotizing enterocolitis <br/ ><br>5. Retinopathy of prematurity <br/ ><br>6. Hematocrit, number of blood transfusions <br/ ><br>7. Significant hyperbilirubinemia <br/ ><br>8. Serum ferritin levels at discharge and 3 months postnatal ageTimepoint: 40 weeks postnatal age, 3 moths postnatal age