Recovery and Symptom Relief Following Percutaneous Ablation of Abdominal Wall Endometriosis

• Conditions: Endometriosis

• Registration Number: NCT06268951
• Lead Sponsor: Mayo Clinic

Brief Summary

To determine the characteristics of recovery and symptom relief following ablation of abdominal wall endometriosis.

Detailed Description

The purpose of this study is to characterize the recovery and symptom relief following cryoablation of abdominal wall endometriosis. Patients undergoing clinically indicated ablation of abdominal wall endometriosis will receive an endometriosis-specific symptom survey (Endometriosis Health Profile - 30) prior to ablation and then at 3-, 6-, 12-, and 24-months following treatment. A 2 question survey related to pain at the treatment site will also be administered prior to ablation and then at 1-, 7-, and 30-days after ablation.

Study Timeline

• Study First Submitted: 2024-02-13
• Study First Submitted QC: 2024-02-19
• Study First Posted: 2024-02-21
• Status Verified: 2024-05
• Study Start: 2024-05-09
• Last Update Submitted: 2024-05-13
• Last Update Posted: 2024-05-16
• Primary Completion: 2027-02
• Study Completion: 2027-12

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

• Undergoing ablation for abdominal wall endometriosis.

Exclusion Criteria

• Decline to participate in research.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Symptom severity due to abdominal wall endometriosis following ablation.	Baseline and intermittently over 24 months	Using the Endometriosis Health Profile - 30 survey, the impact of ablation on endometriosis-related symptoms will be quantified over time. A numerical rating scale will be used to quantify pain at the site of treated abdominal wall endometriosis.

Trial Locations

Locations (1)

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States