Reward and the brain of healthy young adults and healthy older adults.

Completed

Conditions: geen
n.a.

Registration Number: NL-OMON43745

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 48

Inclusion Criteria

Healthy, younger and older Caucasian adults, males and females;
Between18-30 and 60-75 year old;
Right-handed;
Normal (or corrected to normal) vision;
Normal BMI (18-25 kg/m2);
fMRI compatible.

Exclusion Criteria

Not matching any of the inclusion criteria, as well matching any criterion in the fMRI exclusion list, including, but not limited to, claustrophobia, infarctions, epilepsy or family history of epilepsy, presence of metal inside the body, presence of electric/electronic devices inside the body (pacemakers, etc.), presence of intracardial lines, users of non-removable dentures.
Psychoactive medication, including antidepressants, anxiolytic, and anti-epileptic drugs, as well as cannabis, XTC or other recreational drugs, (suspected) Pregnancy, intra-utrine device with metal

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are: the choices participants make on each trial, the<br /><br>switching behaviour of the participants (sequential choices) and the brain<br /><br>activity corresponding to those. The outcome of the study (endpoints) will<br /><br>consist of: the neural mechanisms associated stimulus-reward association<br /><br>updating; a description of the age-related differences in those mechanisms.</p><br>

Secondary Outcome Measures