Comparison of effectiveness of two different antibiotics courses in prevention of unfavourable health results of mother and baby in case of early rupture of membranes
Phase 4
- Conditions
- Health Condition 1: O429- Premature rupture of membranes, unspecified as to length of time between rupture and onset of labor
- Registration Number
- CTRI/2024/04/065733
- Lead Sponsor
- DrJyoti
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
– Patient giving written informed consent
– Singleton pregnancy, PPROM after 24 weeks of gestation & before 37 weeks.
Exclusion Criteria
-Not giving consent
– Conditions requiring expedite delivery or contraindication of conservative management like: Chorioamnionitis
Fetal distress
Placental abruption
Active labour
Study & Design
- Study Type
- PMS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method atency period <br/ ><br>Early neonatal sepsis rate-positive blood culture <br/ ><br>Chorioamnionitis rate <br/ ><br>Timepoint: Latency period-date of randomisation until date of delivery <br/ ><br>Early neonatal sepsis rate- within 3 days of delivery <br/ ><br>Chorioamnionitis rate-from day of randomisation until date of clinical/laboratory Chorioamnionitis diagnosis assessed up to 10 weeks <br/ ><br>
- Secondary Outcome Measures
Name Time Method eonatal weight <br/ ><br>Apgar score <br/ ><br> Neonatal intensive care unit (NICU) admission durationTimepoint: Neonatal weight [ Time Frame: at delivery] grams <br/ ><br> Apgar score [ Time Frame: 1 minute - 5minutes] score from 0 to 10 Other Neonatal intensive care unit (NICU) admission duration [Time Frame: days since delivery until rerelease from NICU, assessed up to 6 months]