Effects of three different medicines for prevention of vomiting after surgery
Not Applicable
- Conditions
- Health Condition 1: H712- Cholesteatoma of mastoid
- Registration Number
- CTRI/2022/11/047639
- Lead Sponsor
- St Johns Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Adults aged 18-59 years posted for middle ear surgeries.
2)ASA 1 and 2 patients with well controlled co-morbidities
Exclusion Criteria
1)Patients already on chronic analgesic medications
2)Obese patients BMI >30
3)Pregnant patients
4)Patients with h/o motion sickness,reflux and previous h/o post operative nausea , vomitting
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of intraoperative use of Propofol, Dexmedetomidine and Magnesium sulphate for controlled hypotension (MAP of 55-65 mmHg) in middle ear surgeriesTimepoint: At 5,10,15,20,30,45,60,78,90,105 and 120 minutes
- Secondary Outcome Measures
Name Time Method To assess oligemic field during the surgery. <br/ ><br>To compare the anaesthetic agent consumption (Oxygen, Air and Isoflurane ) at the end of the surgery. <br/ ><br>To compare the degree of postoperative pain and postoperative nausea and vomiting after Propofol , Dexmedetomidine and Magnesium sulphate in recovery period at 5 minutes, 30 minutes, 1 hour, 2hours and 8 hours. <br/ ><br>Timepoint: A)Oligemic field and anaesthetic agent at the end of surgery <br/ ><br>B) Post operative nausea and vomiting and post operative pain at early(5min,30 min) and late (1 hour , 2 hours and 8 hours)