Comparison postoperative delirium within 24 hours between ketamine and propofol as a main anesthetic agent during cardiopulmonary bypass machine

Phase 2

• Conditions: cardiac surgery; ketamine; perioperative strokedeathre- operation; postoperative delirium; cognitive dysfunction

• Registration Number: TCTR20200324003
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-03-16
• Study Start: 2020-03-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

patients who are elderly (≥65 years old) of both genders.
patients who have less than 4 euroscore.
patient without language barrier.
patients who undergo cardiac operation performed under general anesthesia with cardiopulmonary bypass.

Exclusion Criteria

patients who known preoperative cognitive disorder (dementia, cognitive impairment)
patients who've got positive CAM and RASS
patients who have psychiatric or mental disorder
patients who have cerebrovascular disease or carotid disease
patients who undergo aortic surgery
patients who died intra-operatively or within the first 24 hours after the procedure and re-operative patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative delirium 24 hours post-operation CAM-ICU and Richmond Agitation-Sedation Scale

Secondary Outcome Measures

Name	Time	Method
none none none