跳至主要内容
临床试验/NL-OMON50392
NL-OMON50392招募中不适用

Auto-antibody sequencing in patients with autoimmune myasthenia gravis and pemphigus - Auto-antibody sequencing in patients with autoimmune disease

eids Universitair Medisch Centrum0 个研究点目标入组 80 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
80

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • For myasthenia gravis:
  • 1. Males and females aged between 18 years and older at the time of the
  • blood donation.
  • 2. Patient with ocular or generalized AChR MG, MuSK MG or LEMS; and
  • 3. A positive serologic test for AChR antibodies > 0.5 nmol/l or MuSK
  • antibodies >0.1 nmol/l or VGCC antibodies >20 fmol/l. , For Pemphigus:
  • 1. Males and females aged between 18 years and older at the time of the blood
  • 2. Patient with pemphigus subtypes and
  • 3. A positive serologic test for Dsg1 antibodies > 0.5 nmol/l or Dsg3
  • antibodies >0.1 nmol/l.

排除标准

  • For myasthenia gravis and pemphigus:
  • 1. Any confirmed or suspected immunosuppressive or immunodeficient condition
  • not related to the treatment of MG, including human immunodeficiency virus
  • (HIV) infection, or a family history of congenital or hereditary
  • immunodeficiency.
  • 2. History or evidence of administration of immunoglobulins within 1 month
  • prior to the blood withdrawal.
  • 3. The investigator can exclude patients for this trial which are deemed not
  • suitable for any reason.

研究者

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