A Comparison of Prophylactic Ondansetron plus Phenylephrine and Placebo plus Phenylephrine Intravenous Slow Injection on Vasopressor Consumption, Hypotension and Bradycardia after Spinal Anesthesia in Patients undergoing Cesarean Section : A Randomized, Single-Blind Study

Phase 4

Recruiting

• Conditions: Healthy pregnancy; prophylactic, ondansetron, phenylephrine, hypotension, cesarean section

• Registration Number: TCTR20221001007
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-01
• Study Completion: 2024-03-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. ASA physical status II or III
2. BMI <=30 kg/m2
3. age more than or equal 18 years old
4. singleton
5. term preganancy (GA more than or equal 37 weeks)

Exclusion Criteria

1. ondansetron injection less than 10 mins before SA
2. cerebrovascular disease
3. complicated pregnancy (eg. placenta previa, abruptio placantae)
4. major fetal anomalies
5. history of monoamine oxidase inhibitor (MAOI) use
6. other drugs administration before baby delivery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
vasopressor comsumption before baby delivery case record form

Secondary Outcome Measures

Name	Time	Method
hypotension before baby delivery case record form