Comparison in sedation with remimazolam and dexmedetomidine in transfemoral transcatheter aortic valve implantation under monitored anesthesia care

Not Applicable

Recruiting

Conditions: Diseases of the circulatory system

Registration Number: KCT0008753

Lead Sponsor: The Catholic University of Korea, Eunpyeong St. Mary's Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 34

Inclusion Criteria

Patients who visit Eunpyeong St. Mary's Hospital and undergo TAVI through MAC aged 65 or older

Exclusion Criteria

A prospective patient with percutaneous aortic valve replacement under general anesthesia
A preoperative delirious patient
A patient over the age of ninety
Left ventricular ejection fraction <30%
Patients receiving preoperative circulatory support such as ECMO
Patients with a recent myocardial infarction
Patients with a history of allergies to dexmedetomidine, opioids, and benzodiazepines
Patients with Contraindications for Use of Dexmedetomidine, Remifentanyl, and Remimazolam
Patients receiving dialysis for end-stage renal failure
Severe cirrhosis of Child-Pugh class C

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
change of blood pressure;amount of vasopressor;number of hypotension

Secondary Outcome Measures

Name	Time	Method
Changes in hemodynamic indicators during surgery (cardiac index (CI), pulse pressure variation (PPV), stroke volume variation (SVV), Systemic vascular resistance index (SVRI), stroke volume index (SVI), and cardI index (CPI))