NCT02446327已完成不适用
The Metabolic Road to Diastolic Heart Failure : Diastolic Heart Failure Study (MEDIA-DHF)
Central Hospital, Nancy, France0 个研究点目标入组 47 人开始时间: 2012年1月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 47
- 主要终点
- Cardiovascular Hospitalizations or Cardiovascular Death
研究概览
简要总结
The main objective is to replicate the validation of omics biomarkers of left ventricular diastolic dysfunction in patients with metabolic syndrome.
The aim was to recruit overall 750 patients in Europe (100 for France). Currently, 625 patients were enrolled in Europe and 47 in France.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients 18 years of age or older
- •Signs or symptoms of HF
- •Able and willing to provide freely given written informed consent including analysis of genomics
排除标准
- •Patients with acute myocardial infarction
- •Recent trauma or surgery (< 3 months)
- •Hemodynamically significant valvular disease
- •Serious cerebrovascular disease or stroke in the last 3 months
- •Chronic dialysis
- •Chronic liver disease
- •Chronic infectious (bacterial or viral) disease
- •Any malignant concomitant diseases or a malignant disease in the last 5 years
- •Systemic inflammatory diseases, such as autoimmune diseases, connective tissue diseases or collagenoses
- •Pregnant women
研究组 & 干预措施
Diastolic heart failure cohort
Other
This is a prospective cohort of patients with diastolic heart failure. Blood sampling for biomarker assessment
干预措施: Blood sampling for biomarker assessment (Other)
结局指标
主要结局
Cardiovascular Hospitalizations or Cardiovascular Death
时间窗: 12 months
次要结局
- Heart Failure Hospitalizations(3 months, 6 months, 12 months)
- Other cardiovascular hospitalizations(3 months, 6 months, 12 months)
- Cardiovascular Death(3 months, 6 months, 12 months)
- Non cardiovascular Death(3 months, 6 months, 12 months)
- Non cardiovascular hospitalizations(3 months, 6 months, 12 months)
- Cardiovascular Hospitalizations(3 months, 6 months, 12 months)
研究者
Pr. Nicolas GIRERD
Professor of Medicine (PU-PH)
Central Hospital, Nancy, France
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