Comparison of Ascorbic Acid and Grape Seed Extract in Oxidative Stress Induced by on Pump Heart Surgery

Phase 2

• Conditions: Condition 1: Coronary Atrery Bypass Graft (CABG). Condition 2: Atherosclerotic heart disease. Condition 3: Ischaemic cardiomyopathy.; Ischaemic heart diseases; Atherosclerotic heart disease; Ischaemic cardiomyopathy; I20, I21,

• Registration Number: IRCT138708271460N1
• Lead Sponsor: Tabriz Univ Med Sci

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Inclusion Criteria: Candidates for elective CABG surgery with pump for first time, 3 Vessel Disease (3VD).

Exclusion Criteria

High risk patients, Those who need another heart surgery beside CABG, Urgent patients Diabetics, Ischemic time more than 120 min.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eft Ventricular Ejection Fraction (LVEF). Timepoint: Before and after CABG. Method of measurement: Trans Thoracic Echocardiography (TTE).

Secondary Outcome Measures

Name	Time	Method
Total Antioxidant Capacity (TAC). Timepoint: Before, middle and after CABG. Method of measurement: Biochemistry (blood sample).