A study to assess inadequate neuromuscular recovery in postoperative period immediately on arrival and after 30 minutes of arrival by measuring Train of Four ratios after use of intermediate muscle relaxant intraoperatively

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/09/057759
• Lead Sponsor: Max Superspeciality Hospital

Brief Summary

THIS STUDY IS PROSPECTIVE , OBSERVATIONAL STUDY THAT WILL BE ORGANISED AND CARRIED OUT IN THE DEPARTMENT OF ANAESTHESIOLOGY , MAX SUPER SPECIALITY HOSPITAL ,MOHALI , PUNJAB WITH DUE AUTHORISATION FROM THE INSTITUITIONAL ETHICS COMITTEE AND REVIEW BOARD AND IN COMPLIANCE TO INFORMED , WRITTEN CONSENTS TAKEN FROM THE PATIENTS. THIS STUDY WILL ASSESS POSTOPERATIVE RESIDUAL NEUROMUSCULAR BLOCKADE BY DETERMINING TOF RATIOS IN EARLY AND LATE RECOVERY PERIOD FOLLOWING USE OF INTERMEDIATE MUSCLE RELAXANT. THIS STUDY WILL HELP IN DETERMINING THE EFFECTS OF DURATION OF SURGERY AND ANAESTHESIA,TOTAL INTRAOPERATIVE DOSAGE OF INTERMEDIATE MUSCLE RELAXANT AND TIME INTERVAL BETWEEN LAST DOSE OF MUSCLE RELAXANT AND EXTUBATION  ON POSTOPERATIVE RESIDUAL NEUROMUSCULAR BLOCKADE BY DETERMINING TOF RATIOS IN RECOVERY ROOM .

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-09-15
• Study Start: 2023-09-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 102

Inclusion Criteria

1.ASA physical status I or II 2.Patients who have given consent for study 3.Admission for elective surgery 4.Administration of general anaesthesia for surgery 5.Administration of intermediate muscle relaxant for surgery.

Exclusion Criteria

1.ASA physical status III or more than III 2.Evidence of renal , hepatic , metabolic or neuromuscular diseases 3.Admission for emergency surgery 4.Ejection fraction<50% 5.Patients who refused to give consent for study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate post operative residual neuromuscular blockade by determining TOF ratios in early & late recovery period following use of intermediate muscle relaxant. It will help to determine the effects of duration of surgery & anaesthesia , total intraoperative dosage of intermediate muscle relaxant and time interval between last dose of muscle relaxant and extubation on post operative residual neuromuscular blockade by determining TOF ratios in PACU.	1 year

Secondary Outcome Measures

Name	Time	Method
To determine effects of duration of surgery & anaesthesia & total intraoperative dosage of intermediate muscle relaxant and time interval between last dose of muscle relaxant and extubation on post operative residual neuromuscular blockade in post anaesthesia care unit	1 year

Trial Locations

Locations (1)

Max Superspeciality Hospital; 🇮🇳 Chandigarh, CHANDIGARH, India

Max Superspeciality Hospital

🇮🇳Chandigarh, CHANDIGARH, India

Dr Amrita Kaur Sandhu

Principal investigator

8264144773

sandhuamrita72@gmail.com