Effect of majuphala in the management of pimples.

Phase 2/3

Not yet recruiting

Conditions: Acne vulgaris. Ayurveda Condition: YUVANAPIDAKAÂ (MUKHADUSHIKA),

Registration Number: CTRI/2023/05/052670

Lead Sponsor: National institute of ayurveda department jaipur,Rajasthan

Brief Summary: According to Ayurveda healthy skin is a result of overall healthcondition of an individual. The face is the feature which distinguishes aperson. It is one of the essential parameter for oneâ€™s personality andappearance. The concern of face has taken first place in this present time. Ifit gets any anamoly, it lowers down the confidence of an individual as each andevery one wants to look beautiful.Cosmetology is the science dealing with beautification and havingcertain definite principles. People are using cosmetics not only for curingtheir skin problems but in routine to maintain the skin appearance and beauty.*Mukhadushika* is themost common disease and usually self-limiting condition of teenager and adults.It is described in the *kshudraroga* chapterby *Acharya sushruta* which is causedby vitiation of *kapha, vata, rakta*whichappear on face like a *shalmali* thorn,so called as *yuvanapidik*a / *tarunyapidika* also due its prevalence inyouth1. It is the nearest entity for acne vulgaris. Although itâ€™snot a serious threat to the general health, but the social, psychological andemotional impact of acne makes it a disease for the concern. Acne vulgaris is a chronic inflammatory diseaseof pilo sebaceous follicles characterised by comedons, inflamed pustules ,papules and nodules 2 . There are various factors responsible foracne like hormonal changes, stress, diet, pollution etc. It manifests becauseof physiological disturbances during puberty. This is common illness affecting80% of adolescents during puberty. It affects females more as puberty occursearly in females3. In 2010, acne was estimated to affect 650 millionpeople globally making it the 8th most common disease worldwide4

Thereare ample of formulations available for *Mukhadushika*(Acne),butinstead of using complex formulation ,single drug formulation may be morefeasible and effective. *Majuphala,*due to its easy availabilityand cheaper cost may be the most effective drug to treat *Mukhadushika* along with itâ€™saided benefits like antiageing, skin tightening etc. Also, According to *Nighantu Adarsh*, it is *uttamstambak*, *shleshmnashak, shonitsthapana**,* *and vishaghna**5.*Galls arise on young branches of *Quercusinfectoria*tree6and contains the highest naturally occurring level oftannin (approx 50-70%) 7. Tannins have been used for hundreds ofyears for medical purposes and are currently indispensible in dermatology8.Tannins are natural astringent which makes it best anti-oxidant, antibacterial9, anti-inflammatory10 thus reduces inflammation and tightens poresand therefore reduces acne.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients presenting with signs and symptom of Mukhadushika were selected.
Patients of the age group between 18-40 years were selected irrespective of sex and economical status.
Acne vulgaris specific on face.

Exclusion Criteria

1.The age group < 18 years and > 40 years.
Mukhadushika with other diagnosed skin disorder etc were excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief in Pimples.	30 DAYS

Secondary Outcome Measures

Name	Time	Method
Skin tightening,	De pigmentation

Trial Locations

Locations (1): National institute of ayurveda
🇮🇳
Jaipur, RAJASTHAN, India
National institute of ayurveda
🇮🇳Jaipur, RAJASTHAN, India
DrSomya Watts
Principal investigator
7073654920
wattssomya7.sw@gmail.com