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Comparison of Dexmedetomidine and Midazolam for Intra-op Sedation in TIVA in Children Undergoing Inguinal Hernia Repair

Phase 1
Conditions
Inguinal Hernia
Interventions
Registration Number
NCT05337085
Lead Sponsor
Sheikh Zayed Medical College
Brief Summary

To compare dexmedetomidine and midazolam for intra-op sedation in TIVA in children undergoing inguinal hernia repair. The results of the study if found significant will guide the anesthetist in appropriate choice and dose of sedative drug with highest efficacy and minimum side effects to avoid post operative adverse effects associated with anesthesia

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
185
Inclusion Criteria
  • Male and female paediatric patients In age range neonates to 15 years
  • Planned for elective inguinal hernia repair
  • Patients with uncomplicated hernia With ASA class I or II
Exclusion Criteria
  • Patients undergoing emergency inguinal repair
  • Patients with ASA class III,IV,V or VI
  • Patients present with complicated hernia
  • Patients with BMI above 40kg/m2
  • Patients with any allergy to anesthesia
  • Patients with coagulopathy
  • Patients with narcotic/opioid addiction

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
DexmedetomidineDexmedetomidineInj. Dexmedetomidine (precidex) 200/mcg/2ml given to participants in infusion form for 10 mins of surgery and maintenance dose given till the end of surgery
MidazolamMidazolamInj midazolam 0.5 mg/kg stat dose will be given to participants during surgery
Primary Outcome Measures
NameTimeMethod
Level of sedation assessed through Ramsay Sedation Scale RSS6 months
Secondary Outcome Measures
NameTimeMethod
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