Reproducibility of Magnetic Resonance Myocardial Salvage Index

Completed

• Conditions: Myocardial Infarction
• Interventions: Device: second magnetic resonance imaging scan

• Registration Number: NCT00794300
• Lead Sponsor: University of Leipzig

Brief Summary

The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion strategies in myocardial infarction. As reproducibility of myocardial salvage has not been evaluated appropriately, we aim to scan 20 patients on 2 subsequent days to evaluate reproducibility of myocardial salvage index.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-11-01
• Study First Submitted: 2008-11-19
• Study First Submitted QC: 2008-11-19
• Study First Posted: 2008-11-20
• Primary Completion: 2009-11-01
• Study Completion: 2010-05-01
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-21
• Last Update Posted: 2018-06-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

• ST-elevation myocardial infarction
• Primary percutaneous coronary intervention

Exclusion Criteria

• Contraindications for magnetic resonance imaging

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Acute myocardial infarction patients	second magnetic resonance imaging scan	-

Primary Outcome Measures

Name	Time	Method
Myocardial salvage index reproducibility	2 days

Secondary Outcome Measures

Name	Time	Method
microvascular obstruction reproducibility	2 days
area at risk reproducibility	2 days
infarct size reproducibility	2 days

Trial Locations

Locations (1)

University of Leipzig - Heart Center; 🇩🇪 Leipzig, Germany