Assessment of dynamic cerebral autoregulation in near-infrared-spectroscopy using short-distance channels: a feasibility study in acute ischemic stroke patients

Not Applicable

• Conditions: Acute ischaemic stroke; I63.9; Cerebral infarction, unspecified

• Registration Number: DRKS00029613
• Lead Sponsor: niversitätsklinik für Neurologie Oldenburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-07-06
• Study Start: 2022-07-26
• Results First Posted: 2022-11-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Age at least 18 years
Stroke-typical clinic in the sense of an acute, focal neurological deficit with sudden onset
Ischemic cerebral infarction demonstrated on imaging
Measurement within < 48 hours after infarct event

Exclusion Criteria

Presence of one or more of the following conditions:
Internal carotid artery (ACI) stenosis with > 40% occlusion as defined by NASCET [143].
Disease with severe autonomic nervous system dysfunction.
subdural hematoma or subarachnoid hemorrhage

Stay in intensive care unit within 48 hours of onset of focal neurologic deficit

Person incapable of informed consent and no consent from a legal guardian

Insufficient knowledge of the German language to fully comprehend and assess participant information and no adequate translation possible.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gain and phase shift of (V)LFO, recorded via near infrared spectrosocopy

Secondary Outcome Measures

Name	Time	Method
Clinical applicability in the sense of a feasibility study