Do abnormalities in the control of brain blood flow account for dizziness on standing or after meals in older people?

Not Applicable

Completed

• Conditions: Syncope; Signs and Symptoms; Syncope and collapse

• Registration Number: ISRCTN92525381
• Lead Sponsor: niversity of East Anglia (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03-19
• Last Update Posted: 8 January 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Age >= 60 years, male or female

Exclusion Criteria

1. Known autonomic neuropathy
2. Irregular heart rhythm such as atrial fibrillation
3. On drugs known to affect autonomic function
4. Uncontrolled high blood pressure
5. Stroke
6. Known carotid artery stenosis
7. Severe cognitive impairment
8. Severe physical impairment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Autoregulatory index for baseline, at 1 and 3 minute of tilt and the last 3 and 1 minute of tilt, the duration of which is dependent on the presence or absence of symptoms

Secondary Outcome Measures

Name	Time	Method
1. Arterial stiffness <br>2. Baroreceptor sensitivity