effects of Olive Oil in non-alcoholic fatty liver disease patients
- Conditions
- non-alcoholic fatty liver.Fatty ( change of ) liver , not elsewhere classified
- Registration Number
- IRCT201111022709N20
- Lead Sponsor
- Vice-chancellor for Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria: signing written informed consent, age between 20and 60, diagnosis of non-alcoholic fatty liver disease by fatty infiltration on ultrasound and abnormal serum liver function tests (AST or ALT>30 u/l in men and >20 in women), no smoking, BMI between 25 to 35, no pregnancy or lactation, no use of dietary supplements 2 month prior to enrollment, not having diabetes, , acute heart disease, , other form of liver disease (viral or autoimmune hepatitis, metabolic and hereditary liver disease), no usual use of Olive Oil in dietary pattern, no use of drugs that induces steatosis (amidarone, methotrexate, systemic glucocorticoid, tetracycline, tamoxifen, estrogen, anabolic steroids, valporic acid) , no use of Lipid lowering drugs .
those who are not interested in participating in the study, start using drugs affecting liver functiont, failure to complete or correct use of Olive Oil according to the instruction given , change in recommended diet and daily physical activity
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum ALT. Timepoint: BEFORE AND END OF INTERVENTION. Method of measurement: IFCC,IU/D.;Sserum AST. Timepoint: BEFORE AND END OF INTERVENTION. Method of measurement: IFCC,IU/D.;Steatosis severity. Timepoint: BEFORE AND END OF INTERVENTION. Method of measurement: Sonography.
- Secondary Outcome Measures
Name Time Method