Sedative regimens for drug induced sleep endoscopy in sleep apnea patients.
- Conditions
- Drug-Induced Sleep Endoscopy, Obstructive Sleep Apnea
- Registration Number
- PACTR201706002232945
- Lead Sponsor
- Rehab Said ElKalla
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
both sexes
aged between 18-50 years old
classified as American Society of Anesthesiologists ASA physical status I, II, III,
diagnosed as OSAS by clinical criteria(snoring , morning headache, day sleepiness and tiredness) and polysomnography (apnea hypopnea index>5)
1-Patients who refuse to give informed consent
2-Patients with a baseline oxygen desaturation (resting hypoxemia <95 %)
3-Patients with Mallampati scores of III-IV
4-Patients who are pregnant
5-Patients with frank aspiration history
6-Drug abusers or those having history of chronic anal¬gesic use
7-Patients who known to have allergy against the study drugs,
8-Patients with IInd-IIIrd degree A-V block, pulmonary hypertension ,uncontrolled systemic hypertension, mitral stenosis, aortic stenosis or ischemic heart diseases will be excluded
9-Patients with psychiatric dis¬orders will be also excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method measurement of the incidence of oxygen desaturation among the three groups. Oxygen desaturation is defined as oxygen saturation <90% for more than 30 s, measured using pulse oximetry(9).
- Secondary Outcome Measures
Name Time Method ¿cough reflex (cough and/or sneezing) incidence