Identification of Cardiovascular Risk Factors Linked to Renal Failure Progression
Completed
- Conditions
- Chronic Renal Failure
- Registration Number
- NCT00608998
- Lead Sponsor
- University Hospital, Montpellier
- Brief Summary
The aim of this study is to appreciate the influence of renal failure progression on vasculopathy (coronary calcifications and left ventricular hypertrophy) and cardiovascular risk factors.
- Detailed Description
The aim of this study is to appreciate the relationship between:
* extension of coronary calcifications and chronic renal failure progression
* extension of coronary calcifications and levels of osteoprotegerin (bone disease marker)
* cardiovascular risk factors and coronary calcifications
* cardiovascular risk factors and existence of cardiovascular diseases
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
-
Patient who has signed the written consent form
-
Patient aged > 18 and < 90 years
-
Chronic renal failure defined by glomerular filtration rate (GFR)
- group 1: GFR >90 mL/min with urinary biological abnormalities and GFR comprised between 90 and 60 mL/min
- group 2: GFR comprised between 60 and 30 mL/min
- group 3: GFR <30 mL/min but without dialysis therapy
Exclusion Criteria
- Chronic renal failure patient requiring dialysis therapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method description of osteoprotegerin levels according to chronic renal failure progression inclusion
- Secondary Outcome Measures
Name Time Method relationship between cardiovascular risk factors and cardiovascular disease inclusion osteoprotegerin description according to calcium score inclusion relationship between cardiovascular risk factors and calcium score inclusion calcium score description according to chronic renal failure progression inclusion
Trial Locations
- Locations (1)
Centre Hospitalier Universitaire
🇫🇷Montpellier, France