Comparative study of fractional CO2 laser monotherapy and fractional CO2 laser with injectable Platelet rich plasma in acne scars in a tertiary care centre ,Chengalpattu-A double blinded Randomised control trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 59
- 试验地点
- 1
- 主要终点
- Facial acne scars improvement assesed by Goodman and boron’s quantitative and qualitative acne scar grading scale for each side of the face separately
研究概览
简要总结
Atrophic acne scars are further subclassified into ice pick(60-70%) boxcar(20-30%), and rolling scars(15-25 % ) . Acne scars have significant impact over the patient’s social and psychological aspects of life. There are various treatment options available for acne scars such as chemical peels, dermabration, ablative and non ablative lasers, autologous fat grafting ,radio frequency, punch excision ,punch elevation, punch replacement grafting ,the delay in which leads to redundent scaring making it much more challenging to treat.Although there are various treatments options for treating acne scars ,single modality doesn’t give effective results.
Until now in accordance with the previous studies, there are no definitive treatments to revert the skin to nearly normal . so I would like to combine fractional co2 laser (standard method) with Platelet Rich Plasma in a split face study in patients with acne scars between 18 To 40 yrs by randomised control trial .
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with acne scar >18 yrs with grade 2 to 4, willing to give informed consent .
排除标准
- •1.Those with active inflammation
- •Those who are predisposed to keloid 3.Those with collagen vascular diseases
- •Those with active herpes infection 5.Those not willing to take part in the study.
结局指标
主要结局
Facial acne scars improvement assesed by Goodman and boron’s quantitative and qualitative acne scar grading scale for each side of the face separately
时间窗: At 4wks,8 wks,12 wks and 20 wks
次要结局
- Acne scar improvement graded based on Goodman & boron’s quantitative & qualitative scar grading scale(At 4weeks,8 weeks,12weeks & 20 weeks)