comparison of the efficacy &effectiveness of clomiphen citrate and recombinant FSH in infertile women candidated for IUI

Phase 3

Conditions: female infertility.
Female infertility associated with anovulation

Registration Number: IRCT201211135181N8

Lead Sponsor: Vice Chanceler for Research Tehran university of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 100

Inclusion Criteria

age lower than 40 years ; the first cycle of treatment;primary infertility; duration of infertility <5years; normal uterine cavity and patent fallopian tubes approved in HSG or laparascopy;normal sperm analysis according to WHO criterias(volume 1.5-5 ml; PH>7.2;viscosity<3;sperm concentration>20000000/ml; total sperm count>40000000;motility>50%;forward progresion>2 ; normal morphology>50% ;round cell<5000000/ml;sperm aglutination<2) mild male factor .
Exclusion criteria: moderate to severe endometriosis diagnosed with laparascopy;history of prior abdominal or gynecological surgery;history of PID; history of allergy or contraindication for hormonal drug usage .

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy. Timepoint: 6-7 weeks after IUI(intra uterine insemination). Method of measurement: sonography and geststional sac detection.;Chemical pregnancy. Timepoint: 2-3 weeks after IUI. Method of measurement: labratory test.;Ongoing pregnancy rate. Timepoint: 20 weeks after IUI. Method of measurement: SONOGRAPHY.

Secondary Outcome Measures

Name	Time	Method
Abortion. Timepoint: 20th week of pregnancy. Method of measurement: follow up the patient and do sonography.;Multi gestation pregnancy. Timepoint: 6-7weeks after IUI. Method of measurement: sonography and detection several gestational sacs.;Live birth rate. Timepoint: 36-40th week of pregnancy. Method of measurement: follow up the patient.