Effectiveness of a protocolized de-resuscitation with VExUS scoring along with a standard protocol as compared to a standard protocol alone on the cumulative fluid balance in sepsis patients: A prospective observational study.

Kovai Medical Centre Hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年5月29日

试验速览

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•All patients admitted in the ICU with suspected sepsis as the primary cause of their acute illness as exhibited by 2 or more of the following.
•Systemic Inflammatory Response Syndrome (SIRS) criteria:
•â?ª Temperature of > 38 C or < 36 C
•â?ª Heart rate of > 90/min
•â?ª Respiratory rate of > 20/min or PaCO2 < 32 mm Hg
•â?ª White blood cell count > 12000/mm3 or < 4000/mm3 or >10% immature bands.
•â?ª Known or suspected infection at the time of screening
•â?ª Those patients in ICU within 24 hours of identification or suspicion of sepsis

•â?ª Patients with conditions that may interfere with portal Doppler assessments such as cirrhosis or portal thrombosis
•â?ª Patients with severe chronic kidney disease (estimated glomerular filtration rate <15 mL/min per 1.73 m2 calculated using the Modified Diet in Renal Disease formula).
•â?ª Age < 18 years
•â?ª Hemodynamic instability due to active haemorrhage
•â?ª Acute cerebral vascular event
•â?ª Acute coronary syndrome (excluding elevated troponin thought to be from demand ischemia)
•â?ª Burn patients
•â?ª Those who had cardiac arrest within 24 hours of enrolment and ROSC attained by CPR
•â?ª Pregnancy patients
•â?ª Patients with difficulty in obtaining ultrasound images of sufficient quality to calculate VExUS scoring

发起方

Kovai Medical Centre Hospital