CTRI/2023/05/052965
Not yet recruiting
未知
Effectiveness of a protocolized de-resuscitation with VExUS scoring along with a standard protocol as compared to a standard protocol alone on the cumulative fluid balance in sepsis patients: A prospective observational study.
Kovai Medical Centre Hospital0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: B95-B97- Bacterial and viral infectious agents
- Sponsor
- Kovai Medical Centre Hospital
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients admitted in the ICU with suspected sepsis as the primary cause of their acute illness as exhibited by 2 or more of the following.
- •Systemic Inflammatory Response Syndrome (SIRS) criteria:
- •â?ª Temperature of \> 38 C or \< 36 C
- •â?ª Heart rate of \> 90/min
- •â?ª Respiratory rate of \> 20/min or PaCO2 \< 32 mm Hg
- •â?ª White blood cell count \> 12000/mm3 or \< 4000/mm3 or \>10% immature bands.
- •â?ª Known or suspected infection at the time of screening
- •â?ª Those patients in ICU within 24 hours of identification or suspicion of sepsis
Exclusion Criteria
- •â?ª Patients with conditions that may interfere with portal Doppler assessments such as cirrhosis or portal thrombosis
- •â?ª Patients with severe chronic kidney disease (estimated glomerular filtration rate \<15 mL/min per 1\.73 m2 calculated using the Modified Diet in Renal Disease formula).
- •â?ª Age \< 18 years
- •â?ª Hemodynamic instability due to active haemorrhage
- •â?ª Acute cerebral vascular event
- •â?ª Acute coronary syndrome (excluding elevated troponin thought to be from demand ischemia)
- •â?ª Burn patients
- •â?ª Those who had cardiac arrest within 24 hours of enrolment and ROSC attained by CPR
- •â?ª Pregnancy patients
- •â?ª Patients with difficulty in obtaining ultrasound images of sufficient quality to calculate VExUS scoring
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Evaluation of Efficacy and Safety of Resuscitative Endovascular Balloon Occlusion of the Aorta with standardized protocol; A prospective observational studyRefractory hemorrhagic shockJPRN-UMIN000029760Chiba University150
Not yet recruiting
Not Applicable
A clinical trial to look for benefits of delayed cord clamping against immediate cord clamping in resuscitation of preterm neonates.Health Condition 1: P84- Other problems with newbornCTRI/2024/02/062956ABVIMS and Dr RML Hospital
Not yet recruiting
Phase 1
Efficacy of early fluid resuscitation combined with Chaiqin Chengqi Decoction in treatment of acute pancreatitis: a randomized controlled trial.ITMCTR2000003450West China Hospitial, Sichuan University
Completed
Not Applicable
Comparison of Conventional fluid Resuscitation and Bolus fluid Resuscitation in preoperative optimization of patients with Infantile Hypertrophic Pyloric stenosisInfantile Hypertrophic Pyloric StenosisPreoperative optimizationInfantile Hypertrophic Pyloric StenosisPreoperative optimizationBolus therapyOptimizationTCTR20190512002none100
Completed
Not Applicable
Dispatcher assisted telephone CPR trialISRCTN82347313Record Provided by the NHSTCT Register - 2006 Update - Department of Health1,600