Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Muscle fatigue Protocol

• Registration Number: NCT06331221
• Lead Sponsor: Universidade do Porto

Brief Summary

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

Detailed Description

A randomized controlled crossover trial will be conducted at a biomechanics laboratory with healthy males. All participants will perform with a washout period of 1 week: a control condition (5-minute rest) and 4 local muscle fatigue protocols (concentric of quadriceps; concentric of hamstrings; eccentric of quadriceps; eccentric of hamstrings) in an isokinetic dynamometer at 30º/s. Three maximum voluntary isometric contractions (MVIC) of quadriceps and hamstrings will also be assessed in the beginning of all conditions.

Knee joint position sense will be assessed before and immediately after the fatigue protocols/control condition, through active concentric and eccentric positionings/repositionings, in sitting and prone positions, to a target range of 45º of knee flexion in an isokinetic dynamometer. Surface electromyography electrodes will also be placed on the vastus lateralis and biceps femoris during all procedures.

Study Timeline

• Study Start: 2023-11-02
• Status Verified: 2024-03
• Study First Submitted: 2024-03-19
• Study First Submitted QC: 2024-03-19
• Study First Posted: 2024-03-26
• Primary Completion: 2024-05-05
• Study Completion: 2024-05-15
• Last Update Submitted: 2024-07-09
• Last Update Posted: 2024-07-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 22

Inclusion Criteria

• males aged between 18 and 30 years;
• without current or previous knee pathology or surgery;
• with a low or moderate physical activity level, according to the International Physical Activity Questionnaire;
• normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.

Exclusion Criteria

• those with cardiorespiratory, neurological or vestibular pathologies;
• with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and
• those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Hamstrings_Eccentric	Muscle fatigue Protocol	30 consecutive maximal eccentric contractions of the hamstrings at 30º/s
Hamstrings_Concentric	Muscle fatigue Protocol	30 consecutive maximal concentric contractions of hamstrings at 30º/s
Quadriceps_Eccentric	Muscle fatigue Protocol	40 consecutive maximal eccentric contractions of quadriceps at 30°/s
Quadriceps_Concentric	Muscle fatigue Protocol	40 consecutive maximal concentric contractions of quadriceps at 30º/s

Primary Outcome Measures

Name	Time	Method
Absolute angular error	Change from Baseline (Before) to Immediately after interventions or control (After)	The absolute value of the difference between the target range and the achieved range
Relative angular error	Change from Baseline (Before) to Immediately after interventions or control (After)	The arithmetic difference between the target range and the range achieved
Variable angular error	Change from Baseline (Before) to Immediately after interventions or control (After)	The standard deviation of the 3 repositionings

Trial Locations

Locations (1)

Faculdade de Desporto, Universidade do Porto; 🇵🇹 Porto, Portugal