Comparison of effects of lignocaine and ketamine on pain after surgery.

Phase 3

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2025/04/084875

Lead Sponsor: Datta Meghe Institute of Higher Education and Research

Brief Summary: This study aims to compare the effects of intraoperative infusion ofLignocaine and Ketamine on duration of post-operative analgesia in patientsundergoing Abdominal surgeries under General Anaesthesia. This will be a parallel group randomised trial conducted at Acharya Vinoba Bhave Rural Hospital, Wardha, India. The pain will be assessed at every half an hourly,hourly and three hourly postoperatively till 24 hours.Visual Analogue Scale will be used to assess pain.A total of 80 patients will be enrolled and 40 each will be randomised in two groups.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 80

Inclusion Criteria

Patients with ASA grade I,II,III Patients posted for abdominal surgeries under General Anaesthesia.
Duration of surgery less than 4 Hours.

Exclusion Criteria

Pregnant or breastfeeding women Patients with cardiac, renal, hepatic disease, seizures or other neurological disorders Patients with chronic preoperative opioid use or substance abuse.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intraoperative infusion of Lignocaine prolongs the duration of postoperative analgesia more when compared to Ketamine.	Assessment of pain will be done every half an hourly till 180 minutes postoperatively, followed by every hourly till 9 hours postoperatively.

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Acharya Vinoba Bhave Rural Hospital
🇮🇳
Wardha, MAHARASHTRA, India
Acharya Vinoba Bhave Rural Hospital
🇮🇳Wardha, MAHARASHTRA, India
DrGummalla Abhigna
Principal investigator
8919225606
abhigna.gummalla@gmail.com