Effects of virgin olive oil enriched with phenolic compounds on blood pressure and endothelial function: a randomised double-blind crossover controlled trial

Rovira i Virgili University (Spain)0 个研究点目标入组 30 人开始时间: 2010年2月2日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Healthy volunteers aged 18 to 75 years, either sex
•2. Systolic blood pressure levels upper or equal 120 to 159 mmHg and/or diastolic blood pressure upper or equal 80 to 99 mmHg without antihypertensive treatment

•1. Low density lipoprotein cholesterol (LDL-c) levels upper 189 mg/dL
•2. Triglycerides upper 350 mg/dL (the threshold level to determine LDL-c by the Friedewald formula)
•3. Chronic alcoholism
•4. Body mass index (BMI) upper 30 kg/m^2
•5. Statin treatment prior to initiating the trial and would not have left at least 2 months before starting the study
•6. Antihypertensive treatment prior to initiating the trial and would not have left at least 2 months before starting the study
•7. Having diabetes mellitus (if you develop a blood glucose, fasting, upper 126 mg/dL, should be repeated and confirmed)
•8. Renal disease (plasma creatinine levels upper 1.4 mg/dL for women and upper 1.5 mg/dL for men
•9. Having acute infectious diseases, malignancies, severe liver insufficiency, chronic respiratory insufficiency or associated endocrine diseases
•10. Other conditions such as special nutritional requirements or medications that may affect lipid metabolism or blood pressure
•11. Participate or participating in a clinical trial in the last 3 months
•12. Incapacity to continue in the study
•13. History of gastrointestinal disease that can impair the absorption of nutrients
•14. Suicide attempt

发起方

Rovira i Virgili University (Spain)